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Animal models of human mitochondrial DNA mutations
BACKGROUND: Mutations in mitochondrial DNA (mtDNA) cause a variety of pathologic states in human patients. Development of animal models harboring mtDNA mutations is crucial to elucidating pathways of disease and as models for preclinical assessment of therapeutic interventions. SCOPE OF REVIEW: This...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249501/ https://ncbi.nlm.nih.gov/pubmed/21854831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2011.08.005 |
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