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Current development of the second generation of mTOR inhibitors as anticancer agents

The mammalian target of rapamycin (mTOR), a serine/threonine protein kinase, acts as a “master switch” for cellular anabolic and catabolic processes, regulating the rate of cell growth and proliferation. Dysregulation of the mTOR signaling pathway occurs frequently in a variety of human tumors, and...

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Bibliografski detalji
Glavni autori: Zhou, Hong-Yu, Huang, Shi-Le
Format: Artigo
Jezik:Inglês
Izdano: Sun Yat-sen University Cancer Center 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249493/
https://ncbi.nlm.nih.gov/pubmed/22059905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.011.10281
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