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Rapid De Novo Centromere Formation Occurs Independently of Heterochromatin Protein 1 in C. elegans Embryos
DNA injected into the C. elegans germline forms extrachromosomal arrays that segregate during cell division [1, 2]. The mechanisms underlying array formation and segregation are not known. Here, we show that extrachromosomal arrays form de novo centromeres at high frequency, providing unique access...
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Format: | Artigo |
Sprache: | Inglês |
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2011
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249440/ https://ncbi.nlm.nih.gov/pubmed/22018540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.09.016 |
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