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Rapid De Novo Centromere Formation Occurs Independently of Heterochromatin Protein 1 in C. elegans Embryos

DNA injected into the C. elegans germline forms extrachromosomal arrays that segregate during cell division [1, 2]. The mechanisms underlying array formation and segregation are not known. Here, we show that extrachromosomal arrays form de novo centromeres at high frequency, providing unique access...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yuen, Karen W. Y., Nabeshima, Kentaro, Oegema, Karen, Desai, Arshad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249440/
https://ncbi.nlm.nih.gov/pubmed/22018540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.09.016
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