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Estradiol Regulation of Lipocalin-Type Prostaglandin D Synthase Promoter Activity: Evidence for Direct and Indirect Mechanisms

In the CNS, lipocalin-type prostaglandin D synthase (L-PGDS) is predominantly a non-neuronal enzyme responsible for the production of PGD(2), an endogenous sleep promoting substance. We have previously demonstrated that estradiol differentially regulates L-PGDS transcript levels in the rodent brain....

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Detalhes bibliográficos
Main Authors: Devidze, Nino, Fujimori, Ko, Urade, Yoshihiro, Pfaff, Donald W., Mong, Jessica A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249404/
https://ncbi.nlm.nih.gov/pubmed/20193744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.02.064
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