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Markers of fibrosis and epithelial to mesenchymal transition demonstrate field cancerization in histologically normal tissue adjacent to breast tumors

Previous studies have shown that a field of genetically altered but histologically normal tissue extends 1 cm or more from the margins of human breast tumors. The extent, composition and biological significance of this field are only partially understood, but the molecular alterations in affected ce...

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Detalhes bibliográficos
Main Authors: Trujillo, Kristina A., Heaphy, Christopher M., Mai, Minh, Vargas, Keith M., Jones, Anna C., Vo, Phung, Butler, Kimberly S., Joste, Nancy E., Bisoffi, Marco, Griffith, Jeffrey K
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249233/
https://ncbi.nlm.nih.gov/pubmed/21105047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25788
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