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Impulsive behaviour induced by both NMDA receptor antagonism and GABA(A) receptor activation in rat ventromedial prefrontal cortex

RATIONALE: Previous work has demonstrated a profound effect of N-methyl-d-aspartic acid receptor (NMDAR) antagonism in the infralimbic cortex (IL) to selectively elevate impulsive responding in a rodent reaction time paradigm. However, the mechanism underlying this effect is unclear. OBJECTIVES: Thi...

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Main Authors: Murphy, Emily R., Fernando, Anushka B. P., Urcelay, Gonzalo P., Robinson, Emma S. J., Mar, Adam C., Theobald, David E. H., Dalley, Jeffrey W., Robbins, Trevor W.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249210/
https://ncbi.nlm.nih.gov/pubmed/22101355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2572-1
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