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Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A cross-sectional multicentre study

OBJECTIVE: Opioids are recommended by the World Health Organization for moderate to severe cancer pain. Oxycodone is one of the most commonly used opioids and is metabolized in the liver by CYP3A4 and CYP2D6 enzymes. The aim of this cross-sectional study was to assess the relationship between oxycod...

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Detalhes bibliográficos
Main Authors: Andreassen, Trine Naalsund, Eftedal, Ingrid, Klepstad, Pål, Davies, Andrew, Bjordal, Kristin, Lundström, Staffan, Kaasa, Stein, Dale, Ola
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249195/
https://ncbi.nlm.nih.gov/pubmed/21735164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-011-1093-5
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