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Functional characterization of the human myosin-7a motor domain

Myosin-7a participates in auditory and visual processes. Defects in MYO7A, the gene encoding the myosin-7a heavy chain, are causative for Usher syndrome 1B, the most frequent cause of deaf-blindness in humans. In the present study, we performed a detailed kinetic and functional characterization of t...

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Detalhes bibliográficos
Main Authors: Heissler, Sarah M., Manstein, Dietmar J.
Formato: Artigo
Idioma:Inglês
Publicado em: SP Birkhäuser Verlag Basel 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249170/
https://ncbi.nlm.nih.gov/pubmed/21687988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0749-8
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