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Toward a Systems Biology Perspective on Enzyme Evolution
Large superfamilies of enzymes derived from a common progenitor have emerged by duplication and divergence of genes encoding metabolic enzymes. Division of the functions of early generalist enzymes enhanced catalytic power and control over metabolic fluxes. Later, novel enzymes evolved from ineffici...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249082/ https://ncbi.nlm.nih.gov/pubmed/22069330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R111.254714 |
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