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Efficient GLP-1 gene delivery using two-step transcription amplification plasmid system with a secretion signal peptide and arginine-grafted bioreducible polymer

Glucagon-like peptide (GLP-1) encoding dual plasmid (pDNA) system (TSTA (SP-GLP-1)) which is composed of pβ-Gal4-p65 and pUAS-SP-GLP-1 was constructed to improve the production and secretion of expressed GLP-1 by combining the advantages of signal peptide (SP) and two-step transcription amplificatio...

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Detalhes bibliográficos
Main Authors: Kim, Tae-il, Lee, Minhyung, Kim, Sung Wan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248954/
https://ncbi.nlm.nih.gov/pubmed/21945681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.09.072
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