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Three-dimensional structure of the radial spokes reveals heterogeneity and interactions with dyneins in Chlamydomonas flagella

Radial spokes (RSs) play an essential role in the regulation of axonemal dynein activity and thus of ciliary and flagellar motility. However, few details are known about the complexes involved. Using cryo–electron tomography and subtomogram averaging, we visualized the three-dimensional structure of...

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Auteurs principaux: Barber, Cynthia F., Heuser, Thomas, Carbajal-González, Blanca I., Botchkarev, Vladimir V., Nicastro, Daniela
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248890/
https://ncbi.nlm.nih.gov/pubmed/22072792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-08-0692
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