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Regulation of miR-200c by Nuclear Receptors PPARα, LRH-1 and SHP

We investigated regulation of miR-200c expression by nuclear receptors. Ectopic expression of miR-200c inhibited MHCC97H cell migration, which was abrogated by the synergistic effects of PPARα and LRH-1 siRNAs. The expression of miR-200c was decreased by PPARα/LRH-1 siRNAs and increased by SHP siRNA...

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Bibliografiske detaljer
Main Authors: Zhang, Yuxia, Yang, Zhihong, Whitby, Richard, Wang, Li
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248804/
https://ncbi.nlm.nih.gov/pubmed/22100809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.11.011
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