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Influenza emergence in the face of evolutionary constraints

Different influenza subtypes can evolve at very different rates, but the causes are not well understood. In this paper, we explore whether differences in transmissibility between subtypes can play a role if there are fitness constraints on antigenic evolution. We investigate the problem using a math...

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Detalhes bibliográficos
Main Authors: Kucharski, Adam, Gog, Julia R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248728/
https://ncbi.nlm.nih.gov/pubmed/21775331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2011.1168
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