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Optical recording of action potentials in mammalian neurons using a microbial rhodopsin

Reliable optical detection of single action potentials in mammalian neurons has been one of the longest-standing challenges in neuroscience. Here we achieve this goal by using the endogenous fluorescence of a microbial rhodopsin protein, Archaerhodopsin 3 (Arch) from Halorubrum sodomense, expressed...

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Huvudupphovsmän: Kralj, Joel M., Douglass, Adam D., Hochbaum, Daniel R., Maclaurin, Dougal, Cohen, Adam E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248630/
https://ncbi.nlm.nih.gov/pubmed/22120467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1782
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