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Variable motif utilization in homeotic selector (Hox)–cofactor complex formation controls specificity

Homeotic selector (Hox) proteins often bind DNA cooperatively with cofactors such as Extradenticle (Exd) and Homothorax (Hth) to achieve functional specificity in vivo. Previous studies identified the Hox YPWM motif as an important Exd interaction motif. Using a comparative approach, we characterize...

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Bibliographic Details
Main Authors: Lelli, Katherine M., Noro, Barbara, Mann, Richard S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248519/
https://ncbi.nlm.nih.gov/pubmed/22160705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114118109
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