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Variable motif utilization in homeotic selector (Hox)–cofactor complex formation controls specificity

Homeotic selector (Hox) proteins often bind DNA cooperatively with cofactors such as Extradenticle (Exd) and Homothorax (Hth) to achieve functional specificity in vivo. Previous studies identified the Hox YPWM motif as an important Exd interaction motif. Using a comparative approach, we characterize...

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Detalhes bibliográficos
Main Authors: Lelli, Katherine M., Noro, Barbara, Mann, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248519/
https://ncbi.nlm.nih.gov/pubmed/22160705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114118109
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