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An inhibitory C-terminal region dictates the specificity of A-adding enzymes

For efficient aminoacylation, tRNAs carry the conserved 3′-terminal sequence C-C-A, which is synthesized by highly specific tRNA nucleotidyltransferases (CCA-adding enzymes). In several prokaryotes, this function is accomplished by separate enzymes for CC- and A-addition. As A-adding enzymes carry a...

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Detalhes bibliográficos
Main Authors: Tretbar, Sandy, Neuenfeldt, Anne, Betat, Heike, Mörl, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248509/
https://ncbi.nlm.nih.gov/pubmed/22167803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116117108
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