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MAPK/ERK Signaling Regulates Insulin Sensitivity to Control Glucose Metabolism in Drosophila

The insulin/IGF-activated AKT signaling pathway plays a crucial role in regulating tissue growth and metabolism in multicellular animals. Although core components of the pathway are well defined, less is known about mechanisms that adjust the sensitivity of the pathway to extracellular stimuli. In h...

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Detalhes bibliográficos
Main Authors: Zhang, Wei, Thompson, Barry J., Hietakangas, Ville, Cohen, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248469/
https://ncbi.nlm.nih.gov/pubmed/22242005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002429
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