Mitotic Spindle Orients Perpendicular to the Forces Imposed by Dynamic Shear

Orientation of the division axis can determine cell fate in the presence of morphogenetic gradients. Understanding how mitotic cells integrate directional cues is therefore an important question in embryogenesis. Here, we investigate the effect of dynamic shear forces on confined mitotic cells. We f...

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Bibliographic Details
Main Authors: Fernandez, Pablo, Maier, Matthias, Lindauer, Martina, Kuffer, Christian, Storchova, Zuzana, Bausch, Andreas R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248423/
https://ncbi.nlm.nih.gov/pubmed/22220200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028965
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