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Mitotic Spindle Orients Perpendicular to the Forces Imposed by Dynamic Shear

Orientation of the division axis can determine cell fate in the presence of morphogenetic gradients. Understanding how mitotic cells integrate directional cues is therefore an important question in embryogenesis. Here, we investigate the effect of dynamic shear forces on confined mitotic cells. We f...

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Autori principali: Fernandez, Pablo, Maier, Matthias, Lindauer, Martina, Kuffer, Christian, Storchova, Zuzana, Bausch, Andreas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248423/
https://ncbi.nlm.nih.gov/pubmed/22220200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028965
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