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Comprehensive Gene-Based Association Study of a Chromosome 20 Linked Region Implicates Novel Risk Loci for Depressive Symptoms in Psychotic Illness

BACKGROUND: Prior genomewide scans of schizophrenia support evidence of linkage to regions of chromosome 20. However, association analyses have yet to provide support for any etiologically relevant variants. METHODS: We analyzed 2988 LD-tagging single nucleotide polymorphisms (SNPs) in 327 genes on...

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Autori principali: Bigdeli, T. Bernard, Maher, Brion S., Zhao, Zhongming, van den Oord, Edwin J. C. G., Thiselton, Dawn L., Sun, Jingchun, Webb, Bradley T., Amdur, Richard L., Wormley, Brandon, O'Neill, Francis A., Walsh, Dermot, Riley, Brien P., Kendler, Kenneth S., Fanous, Ayman H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248394/
https://ncbi.nlm.nih.gov/pubmed/22220189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021440
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