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Suppressed Prostate Epithelial Development with Impaired Branching Morphogenesis in Mice Lacking Stromal Fibromuscular Androgen Receptor

Using the cre-loxP system, we generated a new mouse model [double stromal androgen receptor knockout (dARKO)] with selectively deleted androgen receptor (AR) in both stromal fibroblasts and smooth muscle cells, and found the size of the anterior prostate (AP) lobes was significantly reduced as compa...

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Autors principals: Lai, Kuo-Pao, Yamashita, Shinichi, Vitkus, Spencer, Shyr, Chih-Rong, Yeh, Shuyuan, Chang, Chawnshang
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248327/
https://ncbi.nlm.nih.gov/pubmed/22135068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1189
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