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Rare serotype adenoviral vectors for HIV vaccine development

Human adenoviral vectors are being developed for use in candidate vaccines for HIV-1 and other pathogens. However, this approach suffered a setback when an HIV-1 vaccine using an adenovirus type 5 (Ad5) vector failed to reduce, and might even have increased, the rate of HIV infection in men who were...

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Dettagli Bibliografici
Autore principale: Michael, Nelson L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2011
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248308/
https://ncbi.nlm.nih.gov/pubmed/22201675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60988
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