Altered CD4(+) T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals

Depletion of CD4(+) T cells from the gut occurs rapidly during acute HIV-1 infection. This has been linked to systemic inflammation and disease progression as a result of translocation of microbial products from the gut lumen into the bloodstream. Combined antiretroviral therapy (cART) substantially...

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Detalhes bibliográficos
Main Authors: Mavigner, Maud, Cazabat, Michelle, Dubois, Martine, L’Faqihi, Fatima-Ezzahra, Requena, Mary, Pasquier, Christophe, Klopp, Pascale, Amar, Jacques, Alric, Laurent, Barange, Karl, Vinel, Jean-Pierre, Marchou, Bruno, Massip, Patrice, Izopet, Jacques, Delobel, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248296/
https://ncbi.nlm.nih.gov/pubmed/22156200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59011
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