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A Phase I Study of a Combination of Yttrium-90 labeled Anti-CEA Antibody and Gemcitabine in Patients with CEA Producing Advanced Malignancies

PURPOSE: To determine the maximum tolerated dose of combined therapy using an yttrium-90 labeled anti-CEA antibody with gemcitabine in patients with advanced CEA producing solid tumors. EXPERIMENTAL DESIGN: The chimeric human/murine cT84.66 is an anti-CEA intact IgG1, with high affinity and specific...

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Detalhes bibliográficos
Main Authors: Shibata, Stephen, Raubitschek, Andrew, Leong, Lucille, Koczywas, Marianna, Williams, Lawrence, Zhan, Jiping, Wong, Jeffrey Y.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248239/
https://ncbi.nlm.nih.gov/pubmed/19351765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2213
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