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Using quantitative proteomic analysis to understand genotype specific intrinsic drug resistance in melanoma

The discovery of activating BRAF V600E mutations in 50% of all melanoma patients and the development of small molecule BRAF inhibitors looks set to revolutionize the therapy of disseminated melanoma. However, in the recent clinical trial of the BRAF inhibitor, vemurafenib (PLX4032), a significant pe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Koomen, John M., Smalley, Keiran S. M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248164/
https://ncbi.nlm.nih.gov/pubmed/21505227
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