Proteomics plus genomics approaches in primary immunodeficiency: the case of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) is a rare syndrome due to a mutation in the forkhead box protein 3 gene (FOXP3) leading to an impaired regulatory T cell (T(reg)) activity associated both with skewed T helper type 2 (Th2) response and autoreactive phenomena. The...

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Detalhes bibliográficos
Main Authors: Zennaro, D, Scala, E, Pomponi, D, Caprini, E, Arcelli, D, Gambineri, E, Russo, G, Mari, A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Translational Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248093/
https://ncbi.nlm.nih.gov/pubmed/22132891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04492.x
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