Testis-specific miRNA-469 Up-regulated in Gonadotropin-regulated Testicular RNA Helicase (GRTH/DDX25)-null Mice Silences Transition Protein 2 and Protamine 2 Messages at Sites within Coding Region: IMPLICATIONS OF ITS ROLE IN GERM CELL DEVELOPMENT

Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25), a testis-specific member of the DEAD-box family, is an essential post-transcriptional regulator of spermatogenesis. Failure of expression of Transition protein 2 (TP2) and Protamine 2 (Prm2) proteins (chromatin remodelers, essential for sp...

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Detalhes bibliográficos
Main Authors: Dai, Lisheng, Tsai-Morris, Chon-Hwa, Sato, Hisashi, Villar, Joaquin, Kang, Jung-Hoon, Zhang, Jiabao, Dufau, Maria L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248001/
https://ncbi.nlm.nih.gov/pubmed/22086916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.282756
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