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Poly(ADP-ribose) Polymerase 1 (PARP-1) Binds to 8-Oxoguanine-DNA Glycosylase (OGG1)

Human 8-oxoguanine-DNA glycosylase (OGG1) plays a major role in the base excision repair pathway by removing 8-oxoguanine base lesions generated by reactive oxygen species. Here we report a novel interaction between OGG1 and Poly(ADP-ribose) polymerase 1 (PARP-1), a DNA-damage sensor protein involve...

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Detalhes bibliográficos
Main Authors: Noren Hooten, Nicole, Kompaniez, Kari, Barnes, Janice, Lohani, Althaf, Evans, Michele K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247967/
https://ncbi.nlm.nih.gov/pubmed/22057269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.255869
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