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Characterization of a novel PTEN mutation in MDA-MB-453 breast carcinoma cell line
BACKGROUND: Cowden Syndrome (CS) patients with germ line point mutations in the PTEN gene are at high risk for developing breast cancer. It is believed that cells harboring these mutant PTEN alleles are predisposed to malignant conversion. This article will characterize the biochemical and biologica...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3247870/ https://ncbi.nlm.nih.gov/pubmed/22103913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-490 |
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