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Nitric Oxide-Sensitive Guanylyl Cyclase Is Differentially Regulated by Nuclear and Non-Nuclear Estrogen Pathways in Anterior Pituitary Gland

17β-estradiol (E2) regulates hormonal release as well as proliferation and cell death in the pituitary. The main nitric oxide receptor, nitric oxide sensitive- or soluble guanylyl cyclase (sGC), is a heterodimer composed of two subunits, α and β, that catalyses cGMP formation. α1β1 is the most abund...

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Detalhes bibliográficos
Main Authors: Cabilla, Jimena P., Nudler, Silvana I., Ronchetti, Sonia A., Quinteros, Fernanda A., Lasaga, Mercedes, Duvilanski, Beatriz H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247256/
https://ncbi.nlm.nih.gov/pubmed/22216273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029402
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