HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms

BACKGROUND: Infection with human immunodeficiency virus type-1 (HIV)-1 leads to some form of HIV-1-associated neurocognitive disorders (HAND) in approximately half of the cases. The mechanisms by which astrocytes contribute to HIV-1-associated dementia (HAD), the most severe form of HAND, still rema...

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Main Authors: Mamik, Manmeet K, Banerjee, Sugato, Walseth, Timothy F, Hirte, Renee, Tang, Lin, Borgmann, Kathleen, Ghorpade, Anuja
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247131/
https://ncbi.nlm.nih.gov/pubmed/22027397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-145
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