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A comparison of immunogenicity of norovirus GII-4 virus-like particles and P-particles

Norovirus (NoV) -derived virus-like particles (VLPs) resemble empty shells of the virus and NoV P-particles contain only protruding domains of the NoV capsid. Both NoV-derived subviral particles show similar functionality and antigenicity in vitro and are considered to be potential vaccine candidate...

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Autors principals: Tamminen, Kirsi, Huhti, Leena, Koho, Tiia, Lappalainen, Suvi, Hytönen, Vesa P, Vesikari, Timo, Blazevic, Vesna
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246655/
https://ncbi.nlm.nih.gov/pubmed/22044070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03516.x
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