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Cytomegalovirus-specific CD8(+) T cells targeting different peptide/HLA combinations demonstrate varying T-cell receptor diversity

Cytomegalovirus (CMV) infection and reactivation pose a serious threat for patients after haematopoietic stem cell transplantation. We have previously shown that CD8(+) T cells targeting different CMV epitopes correlate with protection at different threshold frequencies in those patients. To investi...

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Autori principali: Giest, Sandra, McWhinnie, Alasdair, Lefranc, Marie-Paule, Little, Ann-Margaret, Grace, Sarah, Mackinnon, Stephen, Madrigal, J Alejandro, Travers, Paul J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246650/
https://ncbi.nlm.nih.gov/pubmed/22044339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03508.x
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