Extremely High Tp53 Mutation Load in Esophageal Squamous Cell Carcinoma in Golestan Province, Iran

BACKGROUND: Golestan Province in northeastern Iran has one of the highest incidences of esophageal squamous cell carcinoma (ESCC) in the world with rates over 50 per 100,000 person-years in both sexes. We have analyzed TP53 mutation patterns in tumors from this high-risk geographic area in search of...

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Autori principali: Abedi-Ardekani, Behnoush, Kamangar, Farin, Sotoudeh, Masoud, Villar, Stephanie, Islami, Farhad, Aghcheli, Karim, Nasrollahzadeh, Dariush, Taghavi, Noushin, Dawsey, Sanford M., Abnet, Christian C., Hewitt, Stephen M., Fahimi, Saman, Saidi, Farrokh, Brennan, Paul, Boffetta, Paolo, Malekzadeh, Reza, Hainaut, Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246475/
https://ncbi.nlm.nih.gov/pubmed/22216294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029488
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