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Functional Induction of the Cystine-Glutamate Exchanger System X(c) (-) Activity in SH-SY5Y Cells by Unconjugated Bilirubin
We have previously reported that exposure of SH-SY5Y neuroblastoma cells to unconjugated bilirubin (UCB) resulted in a marked up-regulation of the mRNA encoding for the Na(+) -independent cystine∶glutamate exchanger System X(c) (−) (SLC7A11 and SLC3A2 genes). In this study we demonstrate that SH-SY5...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3246462/ https://ncbi.nlm.nih.gov/pubmed/22216172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029078 |
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