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Loops Determine the Mechanical Properties of Mitotic Chromosomes

We introduce a new polymer model for mitotic chromosomes. The key assumption of the model is the ability of the chromatin fibre to cross-link to itself due to binding proteins. These protein-chromatin interactions are included by a probabilistic and dynamic mechanism. The hypothesis is motivated by...

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Hlavní autoři: Zhang, Yang, Heermann, Dieter W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246460/
https://ncbi.nlm.nih.gov/pubmed/22216220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029225
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