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In Vitro and In Vivo Efficacy of Monepantel (AAD 1566) against Laboratory Models of Human Intestinal Nematode Infections

BACKGROUND: Few effective drugs are available for soil-transmitted helminthiases and drug resistance is of concern. In the present work, we tested the efficacy of the veterinary drug monepantel, a potential drug development candidate compared to standard drugs in vitro and in parasite-rodent models...

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Autors principals: Tritten, Lucienne, Silbereisen, Angelika, Keiser, Jennifer
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246443/
https://ncbi.nlm.nih.gov/pubmed/22216366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001457
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