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Influence of Viral Vector–Mediated Delivery of Superoxide Dismutase and Catalase to the Hippocampus on Spatial Learning and Memory During Aging

Aims: Studies employing transgenic mice indicate that overexpression of superoxide dismutase 1 (SOD1) improves memory during aging. It is unclear whether the improvement is due to a lifetime of overexpression, decreasing the accumulation of oxidized molecules, or if increasing antioxidant enzymes in...

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Détails bibliographiques
Auteurs principaux: Lee, Wei-Hua, Kumar, Ashok, Rani, Asha, Herrera, Jose, Xu, Jinze, Someya, Shinichi, Foster, Thomas C.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246419/
https://ncbi.nlm.nih.gov/pubmed/21942371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4054
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