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Intercepting Bacterial Indole Signaling with Flustramine Derivatives

Indole signaling is one of the putative universal signaling networks in bacteria. We have investigated the use of desformylflustrabromine (dFBr) derivatives for the inhibition of biofilm formation through modulation of the indole-signaling network in E. coli and S. aureus. We have found dFBr derivat...

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Main Authors: Bunders, Cynthia A., Minvielle, Marine J., Worthington, Roberta J., Ortiz, Minoshka, Cavanagh, John, Melander, Christian
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246311/
https://ncbi.nlm.nih.gov/pubmed/22091927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja209836z
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