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Intercepting Bacterial Indole Signaling with Flustramine Derivatives

Indole signaling is one of the putative universal signaling networks in bacteria. We have investigated the use of desformylflustrabromine (dFBr) derivatives for the inhibition of biofilm formation through modulation of the indole-signaling network in E. coli and S. aureus. We have found dFBr derivat...

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Autori principali: Bunders, Cynthia A., Minvielle, Marine J., Worthington, Roberta J., Ortiz, Minoshka, Cavanagh, John, Melander, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246311/
https://ncbi.nlm.nih.gov/pubmed/22091927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja209836z
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