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Intercepting Bacterial Indole Signaling with Flustramine Derivatives

Indole signaling is one of the putative universal signaling networks in bacteria. We have investigated the use of desformylflustrabromine (dFBr) derivatives for the inhibition of biofilm formation through modulation of the indole-signaling network in E. coli and S. aureus. We have found dFBr derivat...

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Détails bibliographiques
Auteurs principaux: Bunders, Cynthia A., Minvielle, Marine J., Worthington, Roberta J., Ortiz, Minoshka, Cavanagh, John, Melander, Christian
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246311/
https://ncbi.nlm.nih.gov/pubmed/22091927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja209836z
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