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Frequent Infection of Cortical Neurons by JC Virus in patients with Progressive Multifocal Leukoencephalopathy

The human polyomavirus JC (JCV) infects glial cells and causes progressive multifocal leukoencephalopathy (PML), a demyelinating disease of the brain, in immunosuppressed individuals. The extent of JCV infection of neurons is unclear. We determined the prevalence and pattern of JCV infection in grey...

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Main Authors: Wüthrich, Christian, Koralnik, Igor J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246306/
https://ncbi.nlm.nih.gov/pubmed/22157619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31823ede59
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