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Gab Adapter Proteins as Therapeutic Targets for Hematologic Disease
The Grb-2 associated binder (Gab) family of scaffolding/adaptor/docking proteins is a group of three molecules with significant roles in cytokine receptor signaling. Gabs possess structural motifs for phosphorylation-dependent receptor recruitment, Grb2 binding, and activation of downstream signalin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Hindawi Publishing Corporation
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3246295/ https://ncbi.nlm.nih.gov/pubmed/22216034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/380635 |
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