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Increased in vivo inhibition of gene expression by combining RNA interference and U1 inhibition
Inhibition of gene expression can be achieved with RNA interference (RNAi) or U1 small nuclear RNA—snRNA—interference (U1i). U1i is based on U1 inhibitors (U1in), U1 snRNA molecules modified to inhibit polyadenylation of a target pre-mRNA. In culture, we have shown that the combination of RNAi and U...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245954/ https://ncbi.nlm.nih.gov/pubmed/22086952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr956 |
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