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The Two Faces of NF-κB Signaling in Cancer Development and Therapy

Constitutive activation of NF-κB signaling can promote oncogenesis, providing a rationale for anti-cancer strategies that inhibit NF-κB signaling. Two recent publications in Genes & Development provide evidence that, in contexts where pro-survival signals derive from other oncogenes, NF-κB activ...

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Detalhes bibliográficos
Main Authors: Klein, Ulf, Ghosh, Sankar
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245902/
https://ncbi.nlm.nih.gov/pubmed/22094250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.10.026
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