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Roles of the Akt/GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action

Dopamine D(2) receptor antagonism is a unifying property of all antipsychotic drugs in clinical use. Remarkably, the effector molecules through which these medications exert their actions remain poorly characterized. Increasing attention is being focused on Akt/glycogen synthase kinase-3 (GSK-3) and...

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Detalhes bibliográficos
Main Authors: Freyberg, Zachary, Ferrando, Stephen J., Javitch, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245866/
https://ncbi.nlm.nih.gov/pubmed/19917593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2009.08121873
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