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Dysfunctional B-cell activation in cirrhosis due to hepatitis C infection associated with disappearance of CD27+ B-cell population

BACKGROUND: Chronic hepatitis C virus infection is a leading cause of cirrhosis and hepatocellular carcinoma. Both advanced solid tumors and hepatitis C have previously been associated with memory B-cell dysfunction. In this study we sought to dissect the impact of viral infection, cirrhosis and liv...

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Detalhes bibliográficos
Main Authors: Doi, Hiroyoshi, Iyer, Tara K., Carpenter, Erica, Li, Hong, Chang, Kyong-Mi, Vonderheide, Robert H., Kaplan, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245804/
https://ncbi.nlm.nih.gov/pubmed/21932384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24689
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