Eribulin mesylate (halichondrin B Analog E7389) in platinum-resistant and platinum-sensitive ovarian cancer: a two-cohort, phase II study

BACKGROUND: Eribulin mesylate is a tubulin inhibitor with activity superior to paclitaxel in NIH:OVCAR-3 human epithelial ovarian cancer xenograft models. We sought to assess the efficacy of eribulin in platinum-resistant and platinum-sensitive recurrent ovarian cancer. METHODS: Patients with recurr...

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Main Authors: Hensley, Martee L., Kravetz, Sara, Jia, Xiaoyu, Iasonos, Alexia, Tew, William, Pereira, Lauren, Sabbatini, Paul, Whalen, Christin, Aghajanian, Carol A., Zarwan, Corinne, Berlin, Suzanne
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245795/
https://ncbi.nlm.nih.gov/pubmed/21935916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26569
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