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Fast transcription rates of RNA polymerase II in human cells

Averaged estimates of RNA polymerase II (RNAPII) elongation rates in mammalian cells have been shown to range between 1.3 and 4.3 kb min(−1). In this work, nascent RNAs from an integrated human immunodeficiency virus type 1-derived vector were detectable at the single living cell level by fluorescen...

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Détails bibliographiques
Auteurs principaux: Maiuri, Paolo, Knezevich, Anna, De Marco, Alex, Mazza, Davide, Kula, Anna, McNally, Jim G, Marcello, Alessandro
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245692/
https://ncbi.nlm.nih.gov/pubmed/22015688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.196
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