Polymorphisms in complement component 3 (C3F) and complement factor H (Y402H) increase the risk of postoperative neurocognitive dysfunction following carotid endarterectomy

BACKGROUND: Up to 28% of patients undergoing carotid endarterectomy (CEA) are estimated to experience neurocognitive dysfunction following surgery. The complement cascade plays a central role in ischaemia-reperfusion injury. The authors investigated the effect of common polymorphisms in the compleme...

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Main Authors: Gigante, Paul R, Kotchetkov, Ivan S, Kellner, Christopher P, Haque, Raqeeb, Ducruet, Andrew F, Hwang, Brian Y, Solomon, Robert A, Heyer, Eric J, Connolly, E Sander
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245519/
https://ncbi.nlm.nih.gov/pubmed/20841369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2010.211144
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