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Tandem mass spectrometry in discovery of disorders of the metabolome

Genetic disorders of amino acid and fatty acid metabolism can be detected with tandem mass spectrometry (MS/MS). MS/MS screening of mice subjected to chemical mutagenesis defined a new disorder of branched-chain amino acid metabolism resembling human maple syrup urine disease. This approach has gene...

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Hlavní autor: Strauss, Arnold W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC324547/
https://ncbi.nlm.nih.gov/pubmed/14755332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420924
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